Image driven subject-specific finite element models of spinal biomechanics

Subject-specific finite-element modeling of normal aortic valve biomechanics from 3D+t TEE images

In the past decades, developments in transesophageal echocardiography (TEE) have opened new horizons in reconstructive surgery of the aortic valve (AV), whereby corrections are made to normalize the geometry and function of the valve, and effectively treat leaks. To the best of our knowledge, we propose the first integrated framework to process subject-specific 3D+t TEE AV data, determine age-m...

Subject Specific Finite Element Modelling of the Levator Ani

Understanding of the dynamic behaviour of the levator ani is important to the assessment of pelvic floor dysfunction. Whilst shape modelling allows the depiction of 3D morphological variation of the levator ani between different patient groups, it is insufficient to determine the underlying behaviour of how the muscle deforms during contraction and strain. The purpose of this study is to perfor...

Building Finite Element Models to Investigate Zebrafish Jaw Biomechanics.

Skeletal morphogenesis occurs through tightly regulated cell behaviors during development; many cell types alter their behavior in response to mechanical strain. Skeletal joints are subjected to dynamic mechanical loading. Finite element analysis (FEA) is a computational method, frequently used in engineering that can predict how a material or structure will respond to mechanical input. By divi...

Validation of an Automated Method for Generating Subject-Specific Finite Element Models of the Lumbar Spine

Subject-specific Finite Element Models Can Predict Strain in the Human Medialcollateral Ligament under Valgus Loading

INTRODUCTION: Despite the many investigations of ligament function, the exact role of specific ligaments in maintaining joint stability, the cause and effect of injuries, and the efficacy of various reconstructive procedures remain unclear or unknown. This is partially due to inherent measurement limitations of experimental studies. The finite element (FE) method can predict spatial and tempora...